This paper aims to present a generic theoretical framework of interpretation as field of study, ultimately related to and focusing on tourism interpretation and heritage interpretation. It primarily introduce and discusses the international evolution of interpretaion as field and the pillars of interpretation; namely the priciples of interpretation as firstly introduced by Freeman Tilden. Secondly the paper attempts to analyse to what extent modern interpretation is currently experienced in selected Romanian museums through the means of relevant case studies. There are two selected case studies as significant and symbolic institutions for the Romanian museum network: The Peasant Museum – Bucharest and The Memorial of the Victims of Communism and of the Resistance – Sighetul Marmației. Thirdly, the paper drafts a broader picture showing on what extent priciples of interpretation and heritage intepretation are familiar to Romanian museums and how much of them are in use.