This article aims to map the manner in which the first industrial units crystalized in Bucharest and their subsequent dynamic. Another phenomenon considered was the way industrial sites grew and propagated and how the first industrial clusters formed, thus amplifying the functional variety of the city. The analysis was undertaken using Historical GIS, which allowed to integrate elements of industrial history with the location of the most important industrial objectives. Working in GIS meant creating a database with the existing factories in Bucharest, but also those that had existed in different periods. Integrating the historical with the spatial information about industry in Bucharest was preceded by thorough preparations, which included geo-referencing sources (city plans and old maps) and rectifying them. This research intends to serve as an example of how integrating past and present spatial data allows for the analysis of an already concluded phenomenon and also explains why certain present elements got to their current state.